产品货号：
Z32512
中文名称：
CBX3抗体
英文名称：
Anti-CBX3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CBX3 Antibody |
| 指标别名 | CBX3;Chromobox protein homolog 3;HECH;HP1 GAMMA;HP1Hs gamma;Modifier 2 protein |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IP,FCM |
| 基因名称 | CBX3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human HP1 gamma Recognizes and binds histone H3 tails methylated at 'Lys-9',leading to epigenetic repression.May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR).Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
| 实际分子量 | 21KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Chromobox protein homolog 3 is a protein that is encoded by the CBX3 gene in humans.At the nuclear envelope,the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane.The protein encoded by this gene binds DNA and is a component of heterochromatin.This protein also can bind lamin B receptor,an integral membrane protein found in the inner nuclear membrane.The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane.This protein binds histone H3 tails methylated at Lys-9 sites.This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks.Two transcript variants encoding the same protein but differing in the 5' UTR,have been found for this gene. |
| Uniprot ID | Q13185 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocoprecipitation 1:20 Flow cytometry (FCM) 1:20 |
相关搜索：CBX3抗体，CBX3单抗，Anti-CBX3 Antibody